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Note: Compounded medications are an alternative when branded options are unavailable or unsuitable for a patients specific needs
Fifty years of lyase and a moment of truth: sphingosine phosphate lyase from discovery to disease
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17 We pointed to the evidence that the early use of triple therapy combination of metformin, pioglitazone and a GLP-1 RA achieved lower HbA1c, weight loss and much less hypoglycaemia compared with the traditional approach of sequential escalation through metformin, sulfonylurea and insulin, which was associated with significant weight gain
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