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GLP-1 drugs like semaglutide, the active ingredient in Novo Nordisks Ozempic and Wegovy, were originally intended to treat diabetes and didnt become blockbuster prescriptions until doctors realized that they were also potent weight loss aids that seem to re-wire patients relationship to food and satiety
Progress in Retinal and Eye Research, 50, 3466
It's a reliable support system for many users, helping them stay consistent, reduce cravings, and feel more in control of their health
As with all GLP-1 receptor agonists, there are class-level safety considerations to be aware of, based on UK Summary of Product Characteristics (SmPC) for approved agents such as semaglutide (Wegovy): Pancreatitis : If pancreatitis is suspected indicated by severe, persistent abdominal pain, which may radiate to the back treatment should be stopped immediately and urgent medical assessment sought
Rimonabant was authorized in Europe in 2006 as an anti-obesity medication and then withdrawn by the European Medicines Agency (EMA) in 2009 leading to the termination of the development of other cannabinoid receptor 1 (CB1) blockers for obesity [21, 22]
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