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GLP-1 have shown a cardioprotective benefit for HFpEF patients by promoting weight loss, improving insulin sensitivity, decreasing hepatic gluconeogenesis, and diminishing cardiac oxidative stress

Cazzola M, et al

Evidence suggesting possible risk: rodent studies showed clear tumors GLP-1 receptors exist in human thyroid tissue GLP-1 drugs may influence calcitonin production isolated human case reports exist Evidence suggesting lower risk: humans have fewer GLP-1 receptors in thyroid tissue clinical trials did not show a statistically significant increase most cases are anecdotal or isolated The FDAs position: The risk cannot be ruled out

to 5 p.m

If your insurance doesnt cover it or youre paying out of pocket, talk to your doctor about alternatives to Ozempic

GLP-1 RA improves diabetic retinopathy by protecting the Blood-Retinal barrier through GLP-1R-ROCK-p-MLC signaling pathway