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The trial studies the effects of semaglutide - a drug originally intended to reduce effects of diabetes focusing primarily on its effects on major heart disease and strokes versus that of diet and exercise or placebo

Participants receiving apitegromab preserved more lean mass than those receiving placebo while losing similar amounts of weight

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J Agric Food Chem 66:11911196 Pan H-Y, Ye Z-W, Zheng Q-W, Yun F, Tu M-Z, Hong W-G, Chen B-X, Guo L-Q, Lin J-F (2022) Ergothioneine exhibits longevity-extension effect in Drosophila melanogaster via regulation of cholinergic neurotransmission, tyrosine metabolism, and fatty acid oxidation

How much weight can a non-diabetic expect to lose on GLP-1 therapy