However, it is not necessarily a quick reduction in weight
Genetic Predisposition Significantly, 22% of PD cases concur with Dupuytren, a fibrotic disorder implicated in palmar fascia (Nugteren et al., 2011)
This ensures the medication provides meaningful clinical benefit whilst minimising unnecessary exposure to potential adverse effects
The class 1 variant is a rare and severe one, associated with chronic non-spherocytic hemolytic anemia
Most patients tolerate tirzepatide very well, but some may experience nausea, constipation, bloating, or fatigue during the first few weeks
Peer review Peer review information Communications Biology thanks Jason Plemel, Marta Fumagalli and the other, anonymous, reviewer(s) for their contribution to the peer review of this work