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In addition, due to its protein nature it is inactivated in the gastrointestinal tract, not being absorbed (practically null oral bioavailability), which hinders or prevents the passage into plasma of the infant from ingested breast milk (Serrano 2015), except in premature infants and during the immediate neonatal period, in which there may be greater intestinal permeability
Poirier, C., van Effenterre, D., Delord, B., Johannes, L
Unlike older peptides like GHRP-6 or GHRP-2, Ipamorelin has minimal side effects and does not significantly affect cortisol, prolactin, or hunger
PMID: 26700585
This reality does not invalidate therapeutic potential but requires users to assume responsibilities for quality verification that regulatory systems normally handle
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