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A matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) assay revealed several proteins with antioxidant functions including a GST that were differentially expressed between compatible and incompatible interactions, indicating the differential accumulation of ROS in infected tissues (Li et al., 2011)
Furthermore, repeated high-dose injections may alter the balance of antioxidants in the body, potentially triggering oxidative stress rather than reducing it