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2a, b and f, TGF- effectively activated the accumulation of lipid hydroperoxides, such as 4-HNE, C11-BODIPY oxidation, and MDA
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With reduced preload the heart does not have to exert as much contractile force which reduces the oxygen requirements of the heart and also reduces ventricular transmural pressure resulting in reduced compression of the coronary arteries allowing for more efficient blood flow through the heart
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