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Also, pre-incubation with BSO before rotenone exposure did not enhance the cytotoxicity of rotenone (Fig

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As discovered more recently by Zhangs group, NRF2 can also be negatively regulated through the E3 ubiquitin-protein ligase synoviolin (HRD1), recently associated with the ER stress produced by misfolded protein accumulation

An unusual feature reported in the literature is timing: in some studies, DSIP given during the day was associated with improved sleep that night , rather than acting as an immediate, bedtime sedative

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