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Another example is the anti-CD33 antibody calicheamicin conjugate, Mylotarg (Linenberger et al., 2001
Mitogen-activated protein kinases in innate immunity
Cancer Cell 16 , 401412 (2009)
However, it may also cause the darkening of existing moles or the appearance of new ones, raising concerns about skin health monitoring
It is not clear whether these events indicate additional risk or whether they result from preexisting medical illness and concomitant medication use among these patients
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