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Results: In the derivation cohort (1,483 patients): median age was 60 years, 68.6% were male, median BMI was 29.1 kg/m 2 (IQR 26.0-32.0), 32.8% had type 2 diabetes mellitus (T2DM), 60.1% were on antihypertensive therapy, 41.0% used lipid-lowering drugs
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As precedent, they point to Kennedys efforts to reduce the number of vaccines children receive
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The practical rationale for combination protocols is straightforward: BPC-157 targets local tissue repair (particularly GI, musculoskeletal, and neural) through signaling pathways that promote growth factor expression and cell survival at injury sites, while TB-500 operates more systemically particularly through vascular remodeling, cardiac progenitor activation, and direct anti-inflammatory cytokine modulation
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