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Presented for research literature review only LORAIZQUIERDO EC (1964)
2 Synthetic GLP-1RAs are structurally modified analogues engineered to resist dipeptidyl peptidase-4 cleavage, prolonging their half-life
Springer, pp 209221
(8) Based on this data, the peptide may induce peaks that exceed 3-fold the typical physiological peaks that may reach about 20 mU/L
Typical daily range: 200600 mcg once daily (gradual titration)
30 Furthermore, a comparative trial of exenatide and liraglutide in T2DM subjects concluded that both incretin mimetics were associated with a significant reduction in body weight when compared to baseline (2.87 kg and 3.24 kg, respectively)
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