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However, a noticeable effect on weight loss and fat burning will probably take several days to several weeks, depending on the metabolism, age, health, and lifestyle
Stay hydrated, as B vitamins are water-soluble and excess is excreted in urine (briefly bright yellow urine is normal and not concerning)
Most patients start at 300 mcg/day and titrate toward 500 mcg/day
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Avoid tight clothing over the site while it resolves
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