It's one of the most selective GH secretagogues, meaning it stimulates GH with minimal impact on other hormones like cortisol or prolactin
One consequence of this design was it was better at accessing brain GLP-1 receptors
For anyone modeling these intervals, reconstitution math and dose tracking become essential, and tools such as a reconstitution calculator and peptide tracker help keep protocols consistent
Research published in Diabetes, Obesity and Metabolism found that nausea affected 12% to 24% of patients across the SURPASS trials, diarrhea affected 12% to 22%, and vomiting affected 2% to 13%, with these symptoms most commonly appearing during dose escalation periods
DOI: 10.1073/pnas.2426564122
But theyre not exactly the same