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Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance spectroscopy

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Suitable candidates include: Patients with type 2 diabetes and a BMI of 35 kg/m or higher (or 32.5 kg/m or higher for people of South Asian or other minority ethnic backgrounds), or where weight loss would benefit other significant obesity-related comorbidities Those with type 2 diabetes who have not achieved target HbA1c levels with metformin and other oral medications People for whom weight loss would benefit other obesity-related comorbidities or where weight-neutral treatment options are preferred Individuals with occupational implications where insulin therapy would be problematic Importantly, NICE recommends continuing GLP-1 receptor agonist treatment only if there is a beneficial metabolic response: after 6 months, treatment should continue only if HbA1c has decreased by at least 11 mmol/mol (1.0%) and weight has decreased by at least 3% from initial body weight

The Trap: If you add a massive block of expanding fiber to a digestive system that has stopped moving, it doesn't cure the constipationit creates painful bloating, gas, and severe impaction

[84] Hamilton-Reeves J, Rebello S, Thomas W, et al

The pre-operative level of the oxidative stress markers (MDA and SOD) and the apoptosis markers (fas and caspase-3) also did not show any significant difference between the control and L-carnitine groups