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It is a first-in-class dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist
Has delirium or cognitive impairment
Managing GI effects comes down to a few practical approaches
Administration of UDCA results in increased GLP-1 levels, enhanced hepatic expression of the gene (CYP7A1) encoding the rate-limiting enzyme in bile acid synthesis, improved insulin sensitivity, and improved glucose tolerance
Research has identified altered mitochondrial function or energy metabolism in a subgroup of individuals with autism
While effects specifically on endogenous GLP-1 require further research, the overall metabolic benefits of exercise are well-established
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