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In addition, ferroptosis is positively or negatively regulated by several transcription factors, including nuclear factor E2-related factor 2 (NRF2), activating transcription factor 3/4 (ATF3/4), Yes-associated protein 1 (YAP1), and hypoxia-inducible factor l (HIF1A) (28)
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Metabolic-dysfunction-associated fatty liver disease (MAFLD), which is linked to TMAO, can proceed to severe liver disorders and is a known risk factor for several malignancies
10.1093/jn/136.6.1741S 68 JaworskaK.HeringD.MosieniakG.Bielak-ZmijewskaA.PilzM.KonwerskiM.et al (2019)
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