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J.VilstrupH.GeorgeJ.et al (2019)
Most gastroenterologists agree that during acute inflammation or recent flare-ups, starting GLP-1 therapy should be postponed until disease remission is confirmed
There is no current evidence that GLP-1 medications cause this kind of permanent nerve damage [1] [2]
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In people with both type 2 diabetes and obesity, an indirect comparison drawing on the separate SURMOUNT-2 (NCT04657003) and STEP 2 (NCT03552757) trials, rather than a single head-to-head study, reported weight reduction of up to 15.7% with tirzepatide and 10.6% with semaglutide 2.4 mg
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