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In parental animals, pharmacologically mediated reductions in body weight gain and food consumption were observed at all dose levels

To clarify which types of polyubiquitin chain were added to HMOX2 by MITOL, a ubiquitin chain restriction assay using UbiCRest, which utilizes ubiquitin chain-specific deubiquitinating enzymes, was performed 30

Minor contribution of endogenous GLP-1 and GLP-2 to postprandial lipemia in obese men

As mitochondria fail to maintain cellular energy, neuronal survival is compromised, and apoptotic pathways are activated (Davidson et al., 2001) (Figure 1)

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