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Sustained release was one of the first approaches to be assessed in clinical trials, and led to approval of the encapsulated formulation of exenatide: exenatide extended release (ER) ( At Novo Nordisk the idea was to build on reversible binding to albumin as a solution for the systemic protraction of GLP-1 analogs

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Libraries were prepared using the Universal Plus mRNA-seq protocol (Tecan) according to the manufacturers protocol

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One-step cleavage of all acid-labile groups with excess of trifluoroacetic acid (TFA) yielded the tris-trifluoroacetate salt of deprotected linear hexapeptide 11 with all prerequisites for cyclization

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However, prescribing compounded medications requires a firm understanding of the legal and regulatory requirements that shape their use

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