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Using a 1:100 ratio of mg tissue to L KME buffer (20 mM MOPS, 120 mM KCl, and 1 mM EGTA, pH 7.4), tissue was homogenized in 2 s bursts separated by a 2 s rest for a total of 10 s (or 3 cycles) at 16,600 rpm using IKA T25 digital Ultra-Turrax homogenizer

We used FineGray sub-distribution hazard model analyses adjusted for sex and age to assess the association of sociodemographic variables, comorbidities and co-medications (defined in ESM Table 2) with the risk of treatment discontinuation

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The main reason, as you mentioned, is that it is a source from dairy, and there are a whole bunch of reasons why that can be problematic in the eyes of some practitioners

Yale Medicine: What Is the Impact of GLP-1s in Older Adults with Obesity