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(1) Both these findings on chronic and acute action of AOD 9604 suggested that while enhanced beta(3)-AR expression may have played a role in the chronic action of the compound, beta(3)-AR might not be the sole arbiter in this reaction

Metabolic signaling to the nucleus in cancer

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However, in rare casessuch as patients with kidney disease or specific hereditary disorders related to vitamin B12 metabolismhigh doses or inappropriate use could potentially cause complications

Scientists still do not fully understand exactly how AOD-9604 works

In cases of neuropathy caused by vitamin 12 deficiency, supplementation has been seen to improve symptoms