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doi: 10.1016/S2213-8587(14)70225-6 240

MC3R and MC5R activation contribute to energy homeostasis and exocrine gland function, respectively

Consider 2-to-4-week washout before starting tirzepatide 2.5 mg, with close monitoring

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Data from the 2023 Phase 2 retatrutide trial published in the New England Journal of Medicine (NEJM) provide the primary available evidence on the safety and tolerability of retatrutide, including adverse effects such as fatigue

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