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PMID: 26236730 Pickart L, Vasquez-Soltero JM, Margolina A

We also need to watch for any side effects

Long-Term Medication Users Medications such as metformin (used for diabetes) and proton pump inhibitors (used for acid reflux) can interfere with B12 absorption when taken long term, making supplementation necessary

Riboflavin (B2): Essential for energy production and antioxidant support

Other small human reports do not answer the committee question The wider literature includes a 12-person bladder-pain pilot, a very small retrospective knee-pain chart review, and a two-person intravenous safety pilot

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