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The non-DAC version is typically paired with a GHRP (such as ipamorelin) to mimic a natural GH pulse, whereas the DAC version produces a sustained "GH bleed." In a Phase II dose-escalation study by Jett et al., a single injection of CJC-1295 DAC produced a 2- to 10-fold increase in mean 24-hour GH area under the curve (AUC), with effects lasting up to 14 days [1]

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