Tirzepatide works more on your gut and metabolism
GLP-1 medications mimic the natural action of the gut hormone glucagon-like peptide-1 (GLP-1), which regulates blood sugar levels and appetite
Ongoing Phase 3 Trials Several phase 3 trials are underway investigating the efficacy of retatrutide in larger populations (Fig
Foundayo (orforglipron), developed by Eli Lilly, is a new, once-daily oral GLP-1 weight-loss pill approved in the UAE (second globally after the US) and expected to be available from May 2026
Individuals with insulin resistance or type 2 diabetes sometimes respond more slowly in terms of weight loss, though their blood sugar improvements are often faster and more pronounced
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