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TLR signaling pathways In atopic individuals, antigen presenting cells, especially dendritic cells (DCs), recognize allergens

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10.1021/bi970805s 35 JohnsonW

The MALT1 inhibitor MI-2 not only induces ferroptosis in hepatocellular carcinoma cells but also demonstrates synergistic anticancer effects when combined with sorafenib or regorafenib

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We propose that targeting these distinct metabolic checkpoints may offer novel therapeutic approaches for overcoming cancer resistance to immunotherapy