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Description

They mimic the action of the naturally occurring hormone GLP-1, which is involved in regulating blood sugar levels

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GSH synthesis and consumption The synthesis of GSH relies on cysteine as the starting material, and cellular resistance to lipid oxidation depends on intracellular cysteine levels, primarily produced by the system Xc and transsulfuration pathways

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Figure 2 The clinically most relevant and important action of DPP-4 inhibitors is the endogenous elevation of the incretin hormone concentration of GLP-1 that consecutively leads to a glucose-dependent stimulation of insulin secretion and an inhibition of glucagon secretion (10)

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