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Florida, 2011: A dozen individuals in South Florida developed streptococcus endophthalmitis infections after eye injections of bevacizumab prepared by a compounding pharmacy

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Semaglutide was an ideal candidate for oral delivery with SNAC due to its low molecular weight (4,113.6 Da), long half-life (~ 7 days after subcutaneous administration), and high potency relative to other peptides [14, 40, 46, 56]

A reverse switch might require retitration or other adjustments