Berkovic MC, Bilic-Curcic I, Bozek T, Mahecic DH, Majanovic SK, Canecki-Varzic S, et al
People lost up to 24% of their body weight over 48 weeks in Phase 2 trials published in the New England Journal of Medicine in 2023
Bloating and Gas Refined carbohydrates in pizza dough can ferment slightly as they sit longer in the digestive tract
Early research suggests this effect accounts for 2-4% of additional weight loss beyond what dual agonism achieves, a number that compounds significantly over a 48 to 68 week treatment period
Those who had the lifestyle intervention had a reduction of 500 calories per day as well as received a recommended 150 minutes a week of exercise
Consider using an electrolyte supplement like LMNT or Liquid I.V., especially during longer fasts or hot weather