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PMCID: PMC6876937 ) Williams G, Kwan E, Giraldo CN, Lincoln M, Lewin-Smith M (2020) Panniculitis at the site of injection: infection or foreign body reaction

The isocitrate dehydrogenase reaction is the rate-limiting step, as well as the first NADH-yielding reaction of the TCA cycle

I mean, it's just incredibly complex system

Dysregulation of these pathways contributes profoundly to autoimmune pathogenesis by impairing the clearance of damaged organelles and intracellular debris, promoting chronic inflammation, and sustaining autoreactive immune responses

Blood samples were collected from the jugular vein of each horse