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In most people, a good quality B vitamin supplement, and not a shot, is probably the best solution

The Basics: Why Vitamin B12 Matters Vitamin B12 (cobalamin) is more than an "energy vitamin." Your body relies on it for several core functions, and a true deficiency can cause real symptoms

Some practitioners implement cycling approaches (such as 12 weeks on, 4-8 weeks off), though no published research directly compares continuous versus cycled protocols

[108] In addition, certain drugs may interfere with laboratory tests for the vitamin, such as amoxicillin, erythromycin, methotrexate and pyrimethamine

There are different ways to administer medicines or vitamins into the body