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Documented safety note (not instruction): Across the clinical and community literature, darkening of moles and freckles is a documented effect of increased melanogenesis
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19 studies of 1482 articles met the inclusion criteria
Effect of mutation type and location on clinical outcome in 1,013 probands with Marfan syndrome or related phenotypes and FBN1 mutations: an international study
Drug abuse or misuse of these two medications can lead to fatal outcomes
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