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The downside of this is that because your brain needs so much oxygen, its at an increased risk of being exposed to damage caused by oxidation

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However, after escalation to 40 mg, it was decided not to escalate further since it was assessed that the 60 mg dose level would lead to an unacceptable number of AEs

Put the BP lowering and plaque stabilizing effects together and you have a medication that helps prevent heart attacks and strokes especially in those with established heart disease (who are at highest risk for additional cardiovascular events)

The monoclonal antibody was generated using a synthetic peptide as the immunogen and shows reactivity with human samples

Blots were stained with Coomassie Brilliant Blue (CBB) to verify equal loading