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NNMT is a cytosolic S-adenosyl-L-methionine-dependent methyltransferase that converts nicotinamide to 1-methylnicotinamide, spending SAM and diverting nicotinamide away from the NAD+ salvage pathway
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One of the eminent ways they work is reducing the activity of Th17 cells
R., Nakamura, Y., Edwards, K
Cancer J Clin
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