Research on this side effect remains limited
Neither is drug approval, and neither should be read as one
The GHRH analog amplifies the GH-releasing signal, while the secretagogue triggers the actual release
However, achieving deep, systemic changeslike significant improvements in skin tone or long-term immune resilienceusually takes between one and six months
So this is my personal opinion, but you will always have segments of the population that are resistant to using pharmaceuticals or want to try natural solutions first, so products like berberine arent going to go away. As for gut health, which has attracted more awareness as GLP-1 drugs have gained traction, SPINS data show sales of probiotic supplements were down 7.6% in the year to October 6
doi:10.1111/obr.13537 Rojas-Gonzalez A, Figueroa-Hernandez CY, Gonzalez-Rios O, et al