Dulaglutide (TRULICITY) Phonetic pronunciation: DOO la GLOO tide / TRU li si tee Mnemonic: Truly a Doula glue tide US Sales rank: #149 Year of release: 2014 Price range: $735$1000 FDA-approved for: Type 2 diabetes Used off-label for: Weight loss Mechanism: GLP-1 receptor agonist Available doses: 0.75 mg , 1.5 mg, 3 mg , 4.5 mg Dynamic interactions: Glucose lowering Kinetic interactions: Delayed gastric emptying, otherwise none in a bubble Dulaglutide (Trulicity) is a GLP analog that reduces hemoglobin A1C by 1.5% to 1.8%, which is slightly more than other GLP analogs
As with all peptide conjugates containing fatty acid moieties, repeated freeze-thaw cycles should be strictly avoided to preserve the structural integrity of the molecule and the reliability of experimental results
The analysis included 98,147 GLP-1 RA users and approximately 2.49 million DPP-4i users, with a median follow-up ranging from 1.8 to 3.0 years
Taylor K et al
Physical therapy should complement BPC-157 use rather than being replaced by it
Once opened, continue storing in the refrigerator or at room temperature below 86 degrees, but always use within the 21-day window