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while normal dietary intake is considered safe, the effects of high-dose parenteral administration are less well studied

However, while GLP-1 RAs did not exhibit an increased risk of acute pancreatitis, DPP-4 inhibitors demonstrated a notable risk elevation (rate ratio, 1.75) [53]

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[ 1 ] Their work led to the characterization of DSIP, which was published in 1977 after more than a decade of research

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