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The relationship between UGT1A1 gene & various diseases and prevention strategies
Kankuri E, Finckenberg P, Leinonen J, Tarkia M, Bjrk S, Purhonen J, et al
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This comprehensive strategy has the potential to improve not only glycemic control but also overall cardiovascular health, as excessive weight and high blood sugar are risk factors for heart disease
Abbreviations ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index CI: Confidence interval CKD: Chronic kidney disease CVD: Cardiovascular disease eGFR: Estimated glomerular filtration ratio GLP-1RA: Glucagon-like peptide-1 receptor agonist HFpEF: Heart failure with preserved ejection fraction HFrEF: Heart failure with reduced ejection fraction HHF: Heart failure hospitalization HR: Hazard ratio LDL: Low-density lipoprotein LVEF: Left ventricular ejection fraction MACE: Major cardiovascular events MRA: Mineralocorticoid receptor antagonist SGLT2: Sodium-glucose cotransporter 2 References Wong ND, Sattar N
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