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Key Takeaways Drug class: Neurotropic vitamin B12 (active coenzyme cobalamin) Methylcobalamin (B12) Injection treats vitamin B12 deficiency, megaloblastic and pernicious anaemia and peripheral neuropathies including diabetic neuropathy, supporting myelin synthesis and nerve regeneration as the directly usable active coenzyme form of B12

Cloudiness indicates contamination or degradation that compromises both safety and effectiveness

Furthermore, we did not use operationalized criteria (for example, Diagnostic and Statistical Manual 5th edition) to define the populations of interest because these would not be applicable across animal and human studies, but instead relied on the definitions provided by the individual articles

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