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2) The research team of Wekwejt et al employed zebrafish, specifically 3-5 month old longfin phenotype individuals, as a model to investigate the impact of a short-term high-fat (HF) diet on neurobehavioral outcomes and the potential ameliorating effects of MT-II

The consistency of metabolites between positive and negative experiments were also checked (retention time, CCS values, and fold changes)

Exenatide was administered by subcutaneous injection twice a day

No regular IGF-1 monitoring required (unlike full HGH therapy)

10.3390/jcm10061202 28 KiykimE.Aktulu ZeybekA.BarutK.ZbarioluT.CanseverM.Alsancak.et al (2016)

Much of our understanding of their comparative efficacy comes from indirect treatment comparisons or studies with different comparators