doi:10.3390/molecules191119066 Vukojevic J, Milavi M, Perovi D, et al
Things like GHRP3 can potently increase growth hormone, but are known to also potently increase prolactin and cortisol, leading to more than a doubling of circulating cortisol, which depending on how well regulated it is across the time of day can be problematic
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The ratio of cardiac non-myocytes to myocytes, which typically shifts unfavorably with aging, was preserved