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This is the only oral GLP-1 that is FDA approved for primary and secondary MACE reduction in adults with T2DM at high risk for these events, including patients with existing heart disease
Thus, it has been suggested that the hyperglucagonaemia observed with type 2 diabetes may be owing to concurrent liver disease, specifically hepatic steatosis, causing impairment of the liveralpha cell axis (owing to desensitised hepatic GCGR signalling), resulting in hyperaminoacidaemia and, thereby, increased plasma glucagon both in the fasting and postprandial state [99]
Supporting gut function in a practical way
Prioritize protein-rich foods at every meal: eggs, fish, poultry, lean meats, and if tolerated, dairy products
This depends on the prescription filled by the patients provider by healthcare guidelines from the United States National Library of Medicine or Medline Plus and Centers for Disease Control
PMID: 15619630
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