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Although GSH is involved in disulfide formation and protein folding in the ER 25 , our data showed that cystine starvation did not disrupt ER homeostasis in HepG2 cells

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Moreover, overly high NO production in the brain can form peroxynitrite , a potent oxidant that damages neurons and has been implicated in neurodegenerative diseases

10.1016/j.ccell.2015.09.002 Cancer Cell 30 DingB.ZhengP.JiangF.ZhaoY.WangM.ChangM.et al (2020)

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