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Growth hormone deficiency in 'little' mice results in aberrant body composition, reduced insulin-like growth factor-I and insulin-like growth factor-binding protein-3 (IGFBP-3), but does not affect IGFBP-2, -1 or -4
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The mice were tested for hyperglycemia by measuring their blood glucose concentration
In addition, expression of the 1 subunit, which is implicated in sedation, is increased in all strata of the CA3 subregion and in the granule cell layer and hilus of the dentate gyrus
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