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This would be in line with preclinical observations that incretin receptor expression is down-regulated by exposure to high glucose, and improves once normoglycaemia is restored (48), and that dys-regulation of glycaemic control in otherwise healthy humans leads to impaired incretin actions (49)

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Patients may also become upset if there is any deviation from their eating plan, according to Ihlenfeld

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Its important to speak to your doctor about risks, as certain brands of semaglutide drugs may increase heart rates, which may be an issue in people with uncontrolled hypertension, or on ADHD or asthma medications