Research demonstrates that 5-Amino-1MQ exhibits high selectivity for NNMT and does not inhibit structurally related methyltransferases or other enzymes in the NAD+ biosynthesis pathway, including NAMPT and SIRT1
Results from lipotropic B12 injections vary considerably by individual, depending on overall health, lifestyle habits, and specific goals
Possible side effects include injection site pain or redness, mild diarrhea, nausea, itching, headache, or dizziness
Homocysteine Lowering B Vitamins: B12 Shots & B12 Injections: Investigating the Good, Bad, and Alternative
As B12 is a water-soluble vitamin, it's generally considered safe (because any not used will be excreted via your urine), but even so you shouldn't take more than the recommended doses unless recommended to do so by your GP, as some studies have shown possible negative impacts of overdoing it
This is because people might be more motivated to diet or feel other psychological benefits