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biologics use the FDA Purple Book for biosimilar & interchangeable status
Yong Gui Yuan, head of psychosomatics and psychiatry at Southeast University
(2026, April 15th)
Tirzepatide for weight loss is FDA-approved, but only under the brand name Zepbound, which received approval in November 2023 for chronic weight management among adults with obesity or overweight with related health conditions
The extremely long half-life (~12 days) raises additional concerns about compound accumulation with chronic daily dosing
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