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Since both studies were conducted under similar protocols, data from both were combined and reported jointly
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Body Weight, BMI, and Average Weight Loss Outcomes In the phase 2 obesity trial, the 8 mg and 12 mg retatrutide groups had mean body-weight reductions of 22.8% and 24.2% at 48 weeks, respectively [4]
It mimics a hormone your body naturally produces after eating, which tells your brain you are full and signals your pancreas to release insulin
The evidence points toward a combined approach: medication as one part of a broader plan that includes nutrition, movement, and professional support - not a standalone solution
Only a minority of participants chose to discontinue treatment because of hypersensitivity, and discontinuation rates for these reactions were not significantly higher than those observed with placebo groups
