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It is always a subpar amount of each
Another scenario is a patient who has been using a GLP-1 therapy for a few years, has reached a weight-loss plateau, and is now in the maintenance phase of treatment
irritability, anxiety, dysphoria)(Gupta et al, 2023)
Presented for research literature review only Neumann S et al
On top of that, menopause-related sleep disruptions, hot flashes, and mood swings can contribute to extra weight that is hard to lose
In clinical trials where a GLP-1 RA was added to background basal insulin, a general 20% basal insulin reduction in all patients or a 20% reduction in patients with an A1C 8.0%, the GLP-1 RA can be reasonably initiated without a reduction in the basal insulin dose for many patients
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